Press releases

Bionure initiates a Phase 1 clinical trial of its lead compound BN201 in the United Kingdom
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BN201 is a first-in-class selective SGK2 agonist that promotes remyelination and neuroprotection, offering a game-changing solution for neurodegenerative diseases


The company has reconstituted its Board of Directors and added prominent neuro-ophthalmologist Dr. Craig Smith as the new CMO


Barcelona, Spain, May 16, 2018. Bionure, Barcelona based biotech company that develops neuroprotectant agents to treat neurodegenerative diseases primarily focusing on rare ophthalmologic diseases as Acute Optic Neuritis (AON) and Neuromyelitis Optica (NMO), announces today the initiation of a Phase 1 clinical trial of its lead compound BN201 in the United Kingdom.


BN201 is a first-in-class compound that promotes cell survival and endogenous natural repair by activating SKG2, an intracellular serine/threonine kinase that plays a crucial role in the response of neurons to stress and its survival. The Phase 1 clinical trial is intended to investigate safety, tolerability and pharmacokinetics of single and multiple doses of BN201 in healthy volunteers. Results are expected by the end of the year and the company’s plan is to start a Phase 2a trial in 2019.   (...)

Bionure and National Multiple Sclerosis Society Enter into a Collaboration to Support the Development of a New Chemical Entity for Optic Neuritis and Multiple Sclerosis
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MENLO PARK, CA. January 09, 2015. Bionure, Inc. a California-based late-preclinical drug development company, today announced that it has entered into a Sponsored Research Agreement with the National Multiple Sclerosis Society through Fast Forward, its commercial research subsidiary aimed at accelerating the development of new and improved therapies for MS. Under this agreement, Fast Forward will provide funding to Bionure for the late-preclinical development of BN201 to enable IND filling to support the Phase 1 clinical study in Acute Optic Neuritis (AON). Optic neuritis is often a first sign of multiple sclerosis.

Bionure Inc.’s MS Drug Candidate Shows Positive Results for Myelin Repair in Cell Culture Assay
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PALO ALTO, CA. May 27, 2014. Bionure Inc. today announced its drug candidate, BN201, was shown to promote myelination — the cellular process of repairing the protective sheath surrounding nerves that is damaged in people with multiple sclerosis (MS). The pre‐clinical study was conducted in a novel cell culture assay developed by the Myelin Repair Foundation (MRF) and assessed at the Foundation’s Translational Medicine Center under a previously announced collaborative agreement.

The Myelin Repair Foundation Enters First International Partnership with Bionure, Inc.
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SARATOGA, CA. October 31, 2013. The Myelin Repair Foundation (MRF) and Bionure, Inc. today entered a collaborative partnership agreement to advance therapeutics development for Multiple Sclerosis (MS). The Foundation’s unique Accelerated Research Collaboration™ (ARC™) model facilitates collaboration between the top MS leaders worldwide to advance promising compounds into the clinic. In this agreement, the Myelin Repair Foundation will work closely with Bionure, Inc. to assess the neuroprotective capabilities that will promote myelin repair of the company’s proprietary MS therapeutic compound, BN201.